How Long Does Oxycodone Stay in Your System?

Oxycodone is a powerful prescription painkiller, but it can stay in your system for a while after use. 

But a lot of people are asking, “How long does oxycodone stay in your system?” The answer depends on several factors, including metabolism, dosage, and frequency of use. 

In this article, we’d explain more on how your body processes oxycodone and provide more information to help you stay informed and safe.

Learn more about our opioid addiction treatment programs, or call us today at 615-234-9425.

What is Oxycodone?

Oxycodone is a powerful prescription opioid medication primarily used to treat moderate to severe pain. It belongs to a class of drugs known as opioid analgesics, which work by binding to opioid receptors in the brain, spinal cord, and other areas of the body to reduce the sending of pain signals and change how the body perceives pain.

• Oyxcodone is available in immediate-release and extended-release formulations
• Common brand names include OxyContin (extended-release), Roxicodone, and Percocet (which combines oxycodone with acetaminophen)
• Oxycodone is classified as a Schedule II controlled substance in the United States due to its high potential for abuse and dependence
• Side effects can include drowsiness, nausea, constipation, respiratory depression, and euphoria
• Long-term use can lead to physical dependence and tolerance, requiring higher doses to achieve the same pain relief
• It carries risks of addiction and overdose, especially when misused or taken in higher doses than prescribed

How Your Body Breaks Down Oxycodone

Oxycodone is processed in the liver before being eliminated through urine. Most of the drug leaves the body within a day, but traces can stay longer depending on the type of test used.

Oxycodone Detection Times

Different drug tests detect oxycodone for varying lengths of time, they include : 

• Blood Test – Detects oxycodone for up to 24 hours.
• Saliva Test – Can find traces for 1–2 days.
• Urine Test – The most common method, detecting oxycodone for 3–4 days.
• Hair Test – Can show oxycodone use for up to 90 days.

If oxycodone use has become a concern, professional help can make a difference.

At Nashville Treatment Solutions, our addiction treatment programs in Nashville can help you get off oxycodone and begin your recovery journey.

Factors That Affect How Long Oxycodone Stays in Your System

Several factors influence how quickly oxycodone leaves your body, they include : 

• Dosage and Frequency – Higher doses and long-term use lead to longer detection times.
• Metabolism – People with faster metabolisms process drugs more quickly.
• Age and Health – Older adults and those with liver or kidney issues may take longer to eliminate oxycodone.
• Hydration and Activity Levels – Drinking water and staying active can help your body flush out the drug faster.

Why Does Oxycodone Stay in Your System So Long?

Oxycodone has a half-life of 3 to 5 hours, meaning it takes that long for half of the drug to leave your body. However, complete elimination takes multiple half-life cycles, which is why it remains detectable for days or even months in some tests.

Your liver is primarily responsible for metabolizing oxycodone, converting it into noroxycodone and oxymorphone before elimination. Any factors affecting liver function can significantly extend how long the drug remains in your system.

Begin Addiction Treatment in Nashville Today

Oxycodone is highly addictive, and long-term use can lead to dependency. If you or someone you know is struggling, help is available. Don’t wait.

Nashville Treatment Solutions provides compassionate and effective treatment for opioid addiction, guiding you toward a healthier, drug-free life.